Description

2-Fluoro-6-Methoxybenzonitrile is a versatile fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an electron-withdrawing cyano group and an electron-donating methoxy group on a fluorinated benzene ring, makes it a key intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Organic Synthesis & Chemical Research: Employed in academic and industrial R&D labs for Suzuki-Miyaura, Buchwald-Hartwig, and other cross-coupling reactions to create novel chemical entities.
• Fluorine Chemistry Studies: Acts as a model substrate for studying the effects of fluorine substitution on aromatic reactivity and for developing new fluorination methodologies.

Basic Information

Product Name	2-Fluoro-6-Methoxybenzonitrile
CAS No.	94088-46-7
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	2-Fluoro-6-methoxybenzonitrile; 6-Fluoro-2-methoxybenzonitrile; 2-Cyano-3-fluoroanisole; Benzonitrile, 2-fluoro-6-methoxy-; 94088-46-7; 2-Fluoro-6-methoxy-benzonitrile; 2-Methoxy-6-fluorobenzonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Methoxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.