Description

6-Benzyloxy-2-Fluorobenzonitrile is a versatile fluorinated aromatic nitrile building block used in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a benzonitrile core with a benzyloxy and a fluorine substituent, enabling precise modifications in complex molecule construction. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: The nitrile and halogenated aromatic structure makes it a suitable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands, and specialty chemicals with tailored properties.

Basic Information

Product Name	6-Benzyloxy-2-Fluorobenzonitrile
CAS No.	94088-45-6
Molecular Formula	C14H10FNO
Molecular Weight	227.23 g/mol
Synonyms	2-Fluoro-6-(phenylmethoxy)benzonitrile; 2-Fluoro-6-benzyloxybenzonitrile; Benzonitrile, 2-fluoro-6-(phenylmethoxy)-; 6-(Benzyloxy)-2-fluorobenzonitrile; 2-Fluor-6-benzyloxybenzonitril; 94088-45-6; 6-Benzyloxy-2-fluorobenzonitrile
EINECS	Contact for details

Quality Control

Our 6-Benzyloxy-2-Fluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.