Description

(R)-4-Fluorophenylglycine CAS NO 93939-74-3 is a high-purity, non-natural chiral amino acid derivative, serving as a critical building block in asymmetric synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with precise stereochemistry, essential for developing active pharmaceutical ingredients (APIs). This compound is primarily needed by pharmaceutical R&D and manufacturing sectors, as well as by fine chemical producers specializing in advanced intermediates for agrochemicals and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and production of advanced, enantiomerically pure pesticides and herbicides.
• Peptide Chemistry: Incorporated into custom peptides and peptidomimetics for research in medicinal chemistry and biochemistry.
• Asymmetric Catalysis: Serves as a chiral ligand precursor or auxiliary in catalytic reactions to induce stereoselectivity.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Academic & Industrial Research: Utilized in chemical research for studying structure-activity relationships and developing new synthetic methodologies.

Basic Information

Product Name	(R)-4-Fluorophenylglycine
CAS No.	93939-74-3
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	(R)-2-Amino-2-(4-fluorophenyl)acetic acid; D-4-Fluorophenylglycine; (R)-4-Fluorophenylglycine; (R)-α-Amino-4-fluorobenzeneacetic acid; (2R)-2-Amino-2-(4-fluorophenyl)acetic acid; (R)-(-)-4-Fluorophenylglycine; 4-Fluoro-D-phenylglycine; D-4-Fluorophenylglycine
EINECS	Contact for details

Quality Control

Our (R)-4-Fluorophenylglycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.