Description

2,6-Bis(2,2,2-trifluoroethoxy)benzonitrile is a high-value, fluorinated aromatic nitrile building block. This compound matters for its unique combination of a benzonitrile core with trifluoroethoxy substituents, which imparts enhanced lipophilicity, metabolic stability, and electronic properties to advanced molecular architectures. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients, particularly where fluorine incorporation is critical for bioactivity and patent life.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the trifluoroethoxy groups enhance compound efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to engineer specialty polymers with specific thermal, chemical, or surface properties.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalysis and material science applications.
• Chemical Research & Development: Employed as a versatile fluorinated building block in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies.

Basic Information

Product Name	2,6-Bis(2,2,2-trifluoroethoxy)benzonitrile
CAS No.	93624-57-8
Molecular Formula	C11H7F6NO2
Molecular Weight	299.17 g/mol
Synonyms	2,6-Bis(2,2,2-trifluoroethoxy)benzonitrile; 2,6-Bis(trifluoroethoxy)benzonitrile; Benzonitrile, 2,6-bis(2,2,2-trifluoroethoxy)-; 93624-57-8; 2,6-Di(trifluoroethoxy)benzonitrile; 2,6-Bis(2,2,2-trifluoroethoxy)phenyl cyanide
EINECS	Contact for details

Quality Control

Our 2,6-Bis(2,2,2-trifluoroethoxy)benzonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality systems are designed to support cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.