Description

(6α)-17,21-Dihydroxy-6-Methylpregna-1,4,9(11)-Triene-3,20-Dione is a high-purity steroid intermediate of significant importance in advanced pharmaceutical synthesis. This compound serves as a critical building block for the development of novel therapeutic agents, particularly within the fields of endocrinology and anti-inflammatory research. It is essential for R&D laboratories and manufacturing facilities focused on producing specialized corticosteroid analogs and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of advanced corticosteroid drugs and their derivatives.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new steroid-based therapies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Tool compound for studying steroid hormone receptors and related metabolic pathways in vitro.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for complex steroid molecules.

Basic Information

Product Name	(6α)-17,21-Dihydroxy-6-Methylpregna-1,4,9(11)-Triene-3,20-Dione
CAS No.	93269-35-3
Molecular Formula	C22H28O5
Molecular Weight	372.46 g/mol
Synonyms	6α-Methylprednisolone 17,21-Diacetate; 6α-Methyl-δ1,4,9(11)-pregnatriene-17α,21-diol-3,20-dione; 6α-Methylprednisolone 21-acetate 17-propionate (related derivative); 6-Methylprednisolone 17,21-dihydroxy derivative; 9(11)-Dehydro-6α-methylprednisolone; 6α-Methyl-9(11)-dehydroprednisolone; 93269-35-3; 6-Methylpregna-1,4,9(11)-triene-3,20-dione-17,21-diol
EINECS	Contact for details

Quality Control

Our (6α)-17,21-Dihydroxy-6-Methylpregna-1,4,9(11)-Triene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for pharmaceutical R&D and intermediate use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.