Description

18,21-Anhydroaldosterone is a significant steroid derivative and a key synthetic intermediate in the production of various pharmaceutical compounds. This high-purity intermediate is critical for research and development in the synthesis of novel steroid-based therapeutics and reference standards. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic research institutions focused on endocrinology and metabolic disease.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of advanced steroid drugs and active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Biochemical Research: Employed in metabolic pathway studies and research into aldosterone and related hormone mechanisms.
• Process Development: Serves as a starting material or intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.

Basic Information

Product Name	18,21-Anhydroaldosterone
CAS No.	93177-03-8
Molecular Formula	C21H28O4
Molecular Weight	344.45 g/mol
Synonyms	18,21-Anhydroaldosterone; 18,21-Epoxyaldosterone; 11β,21-Dihydroxy-3,20-dioxopregn-4-en-18-al; 18,21-Oxidoaldosterone; Aldosterone 18,21-cyclic acetal; 18,21-Anhydro compound of aldosterone
EINECS	Contact for details

Quality Control

Our 18,21-Anhydroaldosterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed under an inert atmosphere if specified and opened in a low-humidity environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.