Description

4-Cyano-2-Fluoro-Biphenyl is a high-purity, multi-functional biphenyl derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both cyano and fluoro substituents, makes it an essential intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a biphenyl core with halogen and nitrile functionality.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies (LCDs), where the cyano and fluoro groups influence polarity and mesomorphic properties.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport or host materials in OLED devices, leveraging its aromatic structure and electron-withdrawing groups.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct more complex biaryl systems.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and creating specialized chemical libraries.

Basic Information

Product Name	4-Cyano-2-Fluoro-Biphenyl
CAS No.	93129-69-2
Molecular Formula	C₁₃H₈FN
Molecular Weight	197.21 g/mol
Synonyms	2-Fluoro-4-cyanobiphenyl; 4-Cyano-2-fluorobiphenyl; [1,1'-Biphenyl]-4-carbonitrile, 2'-fluoro-; 2'-Fluoro[1,1'-biphenyl]-4-carbonitrile; 2-Fluoro-4-phenylbenzonitrile; 4-(2-Fluorophenyl)benzonitrile; 2-Fluorobiphenyl-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Cyano-2-Fluoro-Biphenyl is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.