Description

Annamycin CAS NO 92689-49-1 is a potent anthracycline antibiotic derivative, structurally related to doxorubicin. This compound is of significant interest in advanced pharmaceutical research due to its unique mechanism of action and potential to overcome multidrug resistance in cancer therapy. It is primarily utilized by research institutions, pharmaceutical developers, and contract manufacturing organizations (CMOs) engaged in oncology drug discovery and development.

Application

• Oncology Research & Drug Discovery: A key investigational agent for studying novel mechanisms to combat drug-resistant cancers.
• Pharmaceutical Intermediate: Serves as a critical building block or precursor in the synthesis of advanced anthracycline-based therapeutics.
• Biochemical Research: Used in in vitro and in vivo studies to understand anthracycline pharmacology and cardiotoxicity profiles.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Preclinical Development: Supports formulation studies, pharmacokinetic/pharmacodynamic (PK/PD) modeling, and safety assessment for new drug candidates.

Basic Information

Item	Detail
Product Name	Annamycin
CAS No.	92689-49-1
Molecular Formula	C32H35NO12
Molecular Weight	625.62 g/mol
Synonyms	4'-O-Benzyladriamycin; 4'-O-Benzyl-14-hydroxydaunomycin; Annamycin (USAN); 4'-O-Benzyl-14-hydroxydaunorubicin; 4'-O-Benzyl-14-hydroxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione; 4'-O-Benzyl-14-hydroxydoxorubicin; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-4'-O-benzyl-5,12-naphthacenedione
EINECS	Contact for details

Quality Control

Our Annamycin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.