Description

Triamcinolone Acetonide 21-Palmitate is a lipophilic ester derivative of the potent corticosteroid triamcinolone acetonide, identified by CAS NO 92626-27-2. This chemical modification enhances its lipid solubility and alters its pharmacokinetic profile, making it a critical intermediate for developing long-acting, depot-formulation pharmaceuticals. It is primarily required by pharmaceutical R&D laboratories and manufacturers specializing in advanced topical, injectable, and transdermal drug delivery systems for anti-inflammatory and immunosuppressive therapies.

Application

• Key intermediate in the synthesis of long-acting corticosteroid prodrugs and depot formulations.
• Research and development of novel topical creams and ointments for dermatological conditions like psoriasis, eczema, and contact dermatitis.
• Development of sustained-release injectable suspensions for intra-articular or soft tissue administration.
• Manufacturing of advanced transdermal patches for controlled drug delivery.
• Production of specialized ophthalmic preparations requiring prolonged anti-inflammatory action.
• Formulation of veterinary pharmaceutical products for long-term anti-inflammatory treatment.

Basic Information

Product Name	Triamcinolone Acetonide 21-Palmitate
CAS No.	92626-27-2
Molecular Formula	C44H69FO7
Molecular Weight	729.02 g/mol
Synonyms	9α-Fluoro-11β,21-dihydroxy-16α,17α-(1-methylethylidene)bis(oxy)pregna-1,4-diene-3,20-dione 21-palmitate; Triamcinolone 16,17-acetonide 21-palmitate; Triamcinolone acetonide palmitate; 21-Palmitoyl triamcinolone acetonide; Fluoxyprednisolone acetonide 21-palmitate
EINECS	Contact for details

Quality Control

Our Triamcinolone Acetonide 21-Palmitate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets stringent standards suitable for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.