Description

(7S-Cis)-9-Acetyl-9-Amino-7-[(2-Deoxy-α-D-Erythro-Pentopyranosyl)Oxy]-7,8,9,10-Tetrahydro-6,11-Dihydroxy-5,12-Naphthacenedione is a structurally complex, semi-synthetic anthracycline derivative of significant research interest. This compound matters as a key intermediate or reference standard in the development of novel chemotherapeutic agents and for advanced pharmacological studies. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) focusing on oncology drug discovery and synthesis.

Application

• Pharmaceutical Intermediate: Critical building block in the synthetic pathway for novel anthracycline-based anticancer drugs.
• Reference Standard: Used for analytical method development, validation, and quality control in API manufacturing.
• Biochemical Research: Serves as a tool compound for studying DNA intercalation mechanisms, topoisomerase II inhibition, and cellular apoptosis pathways.
• Preclinical Development: Employed in the synthesis and evaluation of new drug candidates with potentially improved efficacy or reduced cardiotoxicity profiles.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and cancer biology.

Basic Information

Product Name	(7S-Cis)-9-Acetyl-9-Amino-7-[(2-Deoxy-α-D-Erythro-Pentopyranosyl)Oxy]-7,8,9,10-Tetrahydro-6,11-Dihydroxy-5,12-Naphthacenedione
CAS No.	92395-36-3
Molecular Formula	C25H27NO11
Molecular Weight	517.48 g/mol
Synonyms	9-Acetyl-9-amino-7-[(2-deoxy-α-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-5,12-naphthacenedione; (7S-cis)-9-Acetyl-9-amino-7-O-(2-deoxy-α-D-erythro-pentopyranosyl)-7,8,9,10-tetrahydro-6,11-dihydroxy-5,12-naphthacenedione; 7-Deoxydaunomycinone 9-acetyl-9-amino derivative; A derivative of 7-deoxydaunorubicin; Anthracycline intermediate
EINECS	Contact for details

Quality Control

Our (7S-Cis)-9-Acetyl-9-Amino-7-[(2-Deoxy-α-D-Erythro-Pentopyranosyl)Oxy]-7,8,9,10-Tetrahydro-6,11-Dihydroxy-5,12-Naphthacenedione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) detailing purity, related substances, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.