Description

D-Celiprolol is the dextrorotatory enantiomer of the β-adrenergic receptor blocking agent Celiprolol. This high-purity chiral intermediate is critical for the development and production of enantiomerically pure pharmaceutical actives, where the specific stereochemistry is essential for targeted biological activity and reduced side-effect profiles. It is primarily required by pharmaceutical R&D laboratories and manufacturers specializing in advanced cardiovascular and hypertensive medications.

Application

• As a key chiral building block in the synthesis of enantiopure Celiprolol hydrochloride.
• For research and development of novel β-blockers with improved receptor selectivity.
• In analytical method development as a reference standard for chiral purity testing.
• For pharmacological studies investigating the stereospecific effects of β-adrenergic antagonists.
• In process chemistry for optimizing asymmetric synthesis routes.
• As a starting material for the preparation of deuterated or other labeled analogs for metabolic studies.

Basic Information

Product Name	D-Celiprolol
CAS No.	91878-52-3
Molecular Formula	C20H33N3O4
Molecular Weight	379.50 g/mol
Synonyms	(+)-Celiprolol; D(-)-3-[3-Acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl]-1,1-diethylurea; Dextro-Celiprolol; (R,R)-Celiprolol; UNII-6E5K5P2V8S; BRN 6081702; SC-24665; AY-21011
EINECS	Contact for details

Quality Control

Our D-Celiprolol CAS NO 91878-52-3 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess determination, to ensure it meets high-purity standards suitable for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.