Description

Dl-Bucindolol Hcl CAS NO 91476-01-6 is a non-selective β-adrenergic receptor antagonist (β-blocker) used in pharmaceutical research and development. This compound is of significant interest for its potential therapeutic applications in cardiovascular medicine. It serves as a critical intermediate and reference standard for researchers and manufacturers in the pharmaceutical industry, particularly those focused on developing and analyzing cardiovascular drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced β-blocker drug candidates.
• Reference Standard: Used for analytical method development, validation, and quality control (QC/QA) in pharmaceutical manufacturing.
• Biochemical Research: Employed in pharmacological studies to investigate β-adrenergic receptor binding and function.
• Active Pharmaceutical Ingredient (API) Development: Serves as a starting material for the formulation of potential cardiovascular therapeutics.
• Metabolite Studies: Utilized in research to identify and characterize metabolic pathways and products.
• Impurity Profiling: Acts as a known standard to identify and quantify related substances in drug substances and products.

Basic Information

Item	Detail
Product Name	Dl-Bucindolol Hcl
CAS No.	91476-01-6
Molecular Formula	C22H34N2O3 • HCl
Molecular Weight	410.98 g/mol
Synonyms	Bucindolol Hydrochloride (racemic); (±)-Bucindolol Hydrochloride; 2-[2-Hydroxy-3-[[2-(3-indolyl)-1,1-dimethylethyl]amino]propoxy]benzonitrile Hydrochloride; MJ 13105; DL-Bucindolol HCl; UNII-7J7P7P5J5V; BUCINDOLOL HYDROCHLORIDE (USP); BUCINDOLOL HYDROCHLORIDE (EP)
EINECS	Contact for details

Quality Control

Our Dl-Bucindolol Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting high-grade standards suitable for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.