Description

5-Fluoro-2-Hydroxybenzonitrile is a versatile fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both a nitrile and a hydroxyl group on a fluorinated benzene ring, makes it a valuable building block for creating complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic core for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Research: Serves as a starting material for synthesizing fluorinated compounds used in electronic displays and organic light-emitting diodes.
• Complex Ligand & Catalyst Development: Employed in organometallic chemistry to create specialized ligands for catalytic processes.
• Dye & Pigment Intermediate: Acts as a building block for synthesizing specialized fluorinated dyes and functional pigments.
• Academic & R&D Laboratories: Utilized in fundamental research exploring new fluorination reactions and the properties of fluorinated aromatics.

Basic Information

Product Name	5-Fluoro-2-Hydroxybenzonitrile
CAS No.	91407-41-9
Molecular Formula	C7H4FNO
Molecular Weight	137.11 g/mol
Synonyms	2-Cyano-4-fluorophenol; 4-Fluoro-2-hydroxybenzonitrile; 5-Fluoro-2-hydroxybenzonitrile; 2-Hydroxy-5-fluorobenzonitrile; 5-Fluorosalicylonitrile; 4-Fluorosalicylonitrile; 5-Fluoro-2-cyanophenol; 2-Cyano-4-fluorophenol
EINECS	Contact for details

Quality Control

Our production of 5-Fluoro-2-Hydroxybenzonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation, to ensure it meets precise customer specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, guaranteeing traceability and consistency for your critical R&D and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.