Description

Ebastine is a potent, long-acting, and highly selective second-generation histamine H1-receptor antagonist. This pharmaceutical active ingredient is valued for its efficacy in managing allergic conditions without causing significant sedation. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of anti-allergy medications. Ebastine CAS NO 90729-43-4 represents a critical component for formulators seeking a reliable and effective antihistamine agent.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of oral anti-allergic tablets and syrups.
• Treatment of Allergic Rhinitis: Key component in medications designed to relieve symptoms such as sneezing, rhinorrhea, and nasal itching.
• Management of Chronic Idiopathic Urticaria: Used in products aimed at reducing hives and associated skin irritation.
• Research & Development: Serves as a reference standard and starting material in pharmacological studies and new drug development.
• Generic Drug Manufacturing: Essential for companies producing generic versions of branded antihistamine medications containing ebastine.

Basic Information

Product Name	Ebastine
CAS No.	90729-43-4
Molecular Formula	C32H39NO2
Molecular Weight	469.66 g/mol
Synonyms	4-Diphenylmethoxy-1-[3-(4-tert-butylbenzoyl)propyl]piperidine; Ebastel; Ebastina; CAS 90729-43-4; 1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-1-butanone; 4'--tert-Butyl-4-[4-(diphenylmethoxy)piperidino]butyrophenone
EINECS	Contact for details

Quality Control

Our Ebastine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request. We adhere to current industry best practices to guarantee product consistency and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.