Description

Carebastine is a high-purity pharmaceutical intermediate and active metabolite of the antihistamine ebastine. Its precise chemical structure and consistent quality are critical for ensuring the efficacy and safety of downstream pharmaceutical formulations. This compound is primarily utilized by research institutions and manufacturers in the global pharmaceutical industry for the development and production of advanced antihistamine medications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced antihistamine APIs (Active Pharmaceutical Ingredients).
• Metabolite Reference Standard: Used as an analytical standard in bioanalytical studies and pharmacokinetic research for ebastine.
• Drug Discovery & Development: Employed in preclinical and clinical research for developing new therapeutic agents targeting histamine H1-receptors.
• Quality Control & Analytical Testing: Acts as a certified reference material (CRM) in HPLC and LC-MS methods to ensure batch consistency and purity of final drug products.

Basic Information

Product Name	Carebastine
CAS No.	90729-42-3
Molecular Formula	C32H39NO4
Molecular Weight	501.66 g/mol
Synonyms	4-(4-Benzyipiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-one; Ebastine Carboxylic Acid Metabolite; Carebastin; (±)-Carebastine; 1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(phenylmethyl)-1-piperidinyl]-1-butanone; UNII-9Q5D4S6B3W
EINECS	Contact for details

Quality Control

Our Carebastine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR spectroscopy, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.