Description

Bleomycin Sulfate is a potent glycopeptide antibiotic complex derived from *Streptomyces verticillus*. This compound is a critical active pharmaceutical ingredient (API) valued for its ability to inhibit DNA synthesis and induce strand scission in tumor cells. It is primarily required by pharmaceutical manufacturers and research institutions for the formulation of injectable chemotherapeutic agents and for advanced oncology research. Bleomycin Sulfate CAS NO 9041-93-4 is supplied as a high-purity, lyophilized powder suitable for pharmaceutical development.

Application

• Oncological Drug Formulation: Primary use as the active ingredient in injectable chemotherapy treatments for various cancers, including Hodgkin's lymphoma, testicular cancer, and squamous cell carcinomas.
• Clinical Research & Development: Utilized in preclinical and clinical studies to investigate its efficacy, mechanisms of action, and potential in combination therapies.
• Biochemical Research: Serves as a key reagent in molecular biology and biochemistry labs to study DNA damage, repair mechanisms, and apoptosis (programmed cell death).
• Pharmaceutical Intermediates: Used in the synthesis and development of novel drug conjugates or targeted delivery systems.
• Reference Standard: Acts as a certified reference material (CRM) for quality control and analytical method validation in pharmaceutical testing laboratories.

Basic Information

Item	Detail
Product Name	Bleomycin Sulfate
CAS No.	9041-93-4
Molecular Formula	C55H84N17O21S3 • H2SO4 (for Bleomycin A2 Sulfate)
Molecular Weight	~ 1513.5 g/mol (for Bleomycin A2 Sulfate)
Synonyms	Bleomycin Sulphate; Blenoxane; Bleocin; NSC-125066; Bleomycin A2 Sulfate; Bleomycin B2 Sulfate; Bleomycin Hydrogensulfate; Antibiotic Bleomycin Sulfate; 5'-{[(1S)-1-Phenylethyl]amino}-5'-deoxyadenosine sulfate
EINECS	Contact for details

Quality Control

Our Bleomycin Sulfate is manufactured and tested under strict quality management systems. Each batch is analyzed to meet high-purity standards suitable for pharmaceutical applications, with specifications typically aligned with pharmacopeial guidelines. Certificates of Analysis (COA) documenting identity, purity, potency, and related substances are provided to ensure full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under controlled, dry conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Potency	≥ 1.5 U/mg
pH (1% solution)	4.5 - 6.0
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Bacterial Endotoxins	< 5.0 EU/mg
Sterility (where applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.