Description

Luteinizing Hormone Releasing Hormone (LHRH) is a critical decapeptide neurohormone that plays a fundamental role in the hypothalamic-pituitary-gonadal axis. Its primary commercial and research value lies in its ability to stimulate the synthesis and release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary. This product is essential for manufacturers and research institutions in the pharmaceutical, biotechnology, and veterinary medicine sectors, particularly for the development of diagnostic assays, therapeutic analogs, and reproductive health research.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of LHRH agonists (e.g., Leuprolide, Goserelin) and antagonists used in treating hormone-sensitive cancers (prostate, breast) and endometriosis.
• Research & Diagnostic Reagent: Used in biochemical and physiological research to study reproductive endocrinology, and as a standard or component in immunoassay kits for hormone level measurement.
• Veterinary Medicine: Applied in animal reproduction management for inducing ovulation and synchronization of estrus cycles in livestock.
• Reference Standard: Serves as a high-purity calibrant in quality control laboratories for pharmacopeial testing (USP, EP) of related peptide therapeutics.
• Biotechnology Development: Utilized in cell culture studies and the development of novel drug delivery systems targeting the LHRH receptor.

Basic Information

Product Name	Luteinizing Hormone Releasing Hormone
CAS No.	9034-38-2
Molecular Formula	C55H75N17O13
Molecular Weight	1182.3 g/mol
Synonyms	LHRH; Gonadotropin-Releasing Hormone (GnRH); Luliberin; Gonadorelin; Factrel®; Fertagyl®; Cystorelin®; Pyro-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2; Gonadotropin Releasing Factor
EINECS	Contact for details

Quality Control

Our Luteinizing Hormone Releasing Hormone is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification by HPLC and MS, purity assay, and tests for related substances and residual solvents, ensuring it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) detailing all test results are provided to guarantee traceability, consistency, and compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Biological Activity	Assessed by in vitro assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.