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Lhrh, n-Ac(2)-Nal(1)-4-Cl-Phe(2)-3-Pal(3)-Arg(5)-5-(4-Methoxyphenyl)-5-Oxo-2-Aminopentanoic Acid(6)-Ala(10)- CAS NO 119018-01-8


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CAS No.:119018-01-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Lhrh, n-Ac(2)-Nal(1)-4-Cl-Phe(2)-3-Pal(3)-Arg(5)-5-(4-Methoxyphenyl)-5-Oxo-2-Aminopentanoic Acid(6)-Ala(10)- is a highly specialized, nonapeptide analog of Luteinizing Hormone-Releasing Hormone (LHRH) with a modified structure designed for enhanced stability and specific receptor binding. This compound is critical for advanced research in endocrinology and the development of targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on oncology, reproductive medicine, and neuroendocrinology.

Application

  • Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in the development of novel LHRH antagonist or agonist therapies.
  • Oncology Studies: Used in preclinical and clinical research for hormone-dependent cancers, such as prostate and breast cancer, to study mechanisms of hormone suppression.
  • Endocrinology Research: A vital tool for investigating the hypothalamic-pituitary-gonadal axis, receptor-ligand interactions, and signal transduction pathways.
  • Peptide Chemistry & Biochemistry: Employed as a model compound for studying peptide stability, metabolism, and structure-activity relationships (SAR).
  • Diagnostic Development: Potential use in the formulation of diagnostic kits or assays for measuring hormonal levels or receptor status.
  • Veterinary Medicine: Applied in research for animal reproduction control and the treatment of hormone-related conditions in livestock and companion animals.

Basic Information

Item Detail
Product Name Lhrh, n-Ac(2)-Nal(1)-4-Cl-Phe(2)-3-Pal(3)-Arg(5)-5-(4-Methoxyphenyl)-5-Oxo-2-Aminopentanoic Acid(6)-Ala(10)-
CAS No. 119018-01-8
Molecular Formula C64H84ClN15O13
Molecular Weight 1266.88 g/mol
Synonyms Ac-D-Nal(1)-4-Cl-D-Phe(2)-D-Pal(3)-Arg(5)-D-(p-MeO)Bpa(6)-D-Ala(10)-LHRH; LHRH Antagonist Analog; Cetrorelix Acetate Related Compound; GnRH Antagonist Peptide; (Ac-D-2-Nal1, D-4-Cl-Phe2, D-3-Pal3, Arg5, D-(p-MeO)Bpa6, D-Ala10)-LHRH; Gonadorelin (6-D-(p-methoxybenzoyl)-2-D-2-naphthylalanyl) Derivative; 5-Oxo-2-[[(phenylmethoxy)carbonyl]amino]pentanoic Acid-Containing LHRH Analog
EINECS Contact for details

Quality Control

Our Lhrh analog is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Retention time corresponds to reference standard
Identification (MS) Consistent with molecular weight
Purity (HPLC) ≥ 95.0%
Single Impurity (HPLC) ≤ 2.0%
Water Content (KF) ≤ 5.0%
Peptide Content ≥ 80.0%
Acetate Content (HPLC) Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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