Description

Prazarelix Acetate CAS NO 134485-10-2 is a synthetic peptide derivative, specifically a gonadotropin-releasing hormone (GnRH) antagonist. This compound is of significant interest in advanced pharmaceutical research and development due to its targeted mechanism of action. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents for endocrine-related conditions.

Application

• Pharmaceutical R&D: Serves as a key active pharmaceutical ingredient (API) or intermediate in preclinical and clinical research for hormone-dependent therapies.
• Endocrinology Research: Used as a reference standard or tool compound in laboratory studies investigating GnRH receptor pathways and hormone regulation.
• Therapeutic Agent Development: A critical component in formulating potential treatments for conditions such as prostate cancer, endometriosis, and assisted reproductive technologies.
• Biochemical Assays: Employed in in vitro assays to study receptor binding affinity, antagonistic activity, and pharmacokinetic properties.
• Process Chemistry & Scale-up: Supplied for process development, optimization, and manufacturing scale-up activities within GMP environments.

Basic Information

Product Name	Prazarelix Acetate
CAS No.	134485-10-2
Molecular Formula	C82H103ClN18O13 • xC2H4O2
Molecular Weight	Contact for details
Synonyms	Prazarelix; PPI-149; PPI 149; Ac-D-2Nal-D-4Cpa-D-3Pal-Ser-4Aph(L-hydroorotyl)-D-4Aph(carbamoyl)-Leu-ILys-Pro-D-Ala-NH2 acetate; GnRH Antagonist PPI-149; Azaline B; FE 200486 (related analog); Cetrorelix Acetate (structural analog)
EINECS	Contact for details

Quality Control

Our Prazarelix Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 1.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Acetate Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.