Description

Cetrorelix is a synthetic decapeptide and a potent gonadotropin-releasing hormone (GnRH) antagonist. This compound is critical for its ability to provide immediate and reversible suppression of gonadotropin secretion, offering a significant advantage in controlled therapeutic protocols. It is primarily utilized in the pharmaceutical and biotechnology sectors for advanced clinical research and therapeutic development.

Application

• Pharmaceutical Active Ingredient (API): Used in the formulation of injectable drugs for fertility control and assisted reproductive technologies (ART).
• Clinical Research: Serves as a key reference standard and investigational compound in endocrinology and oncology studies.
• Hormone-Dependent Condition Management: Applied in research for treating conditions such as endometriosis, uterine fibroids, and prostate cancer.
• In Vitro Diagnostics (IVD): Employed in the development of immunoassay kits and diagnostic reagents for hormone level detection.
• Peptide Synthesis & Biochemistry: Acts as a high-purity intermediate or building block for further chemical modification and peptide research.

Basic Information

Product Name	Cetrorelix
CAS No.	145672-81-7
Molecular Formula	C₇₀H₉₂ClN₁₇O₁₄
Molecular Weight	1431.0 g/mol
Synonyms	Cetrorelix Acetate; Cetrotide® (brand name); Ac-D-Nal-D-Cpa-D-Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH₂ acetate; [Ac-D-2-Nal1, D-4-Cpa2, D-3-Pal3, D-Cit6, D-Ala10]-LHRH; Gonadotropin-Releasing Hormone Antagonist (GnRH Antagonist); Azaline B (related analog); Decapeptide GnRH antagonist
EINECS	Contact for details

Quality Control

Our Cetrorelix is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, peptide content determination, and stringent controls for related substances and residual solvents. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with pharmaceutical-grade standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Peptide Content	≥ 80.0%
Acetic Acid Content	5.0% - 12.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.