Description

Prazarelix CAS NO 134457-28-6 is a synthetic decapeptide antagonist of gonadotropin-releasing hormone (GnRH). This compound is of significant interest in pharmaceutical research and development due to its potent and selective mechanism of action. It is primarily utilized by researchers and manufacturers in the life sciences sector for the development of novel therapeutic agents targeting hormone-dependent conditions.

Application

• Pharmaceutical Research: As a key intermediate or reference standard in the development of GnRH antagonist-based therapies.
• Preclinical Studies: For investigating the efficacy and pharmacokinetics of GnRH modulation in animal models.
• Biochemical Assays: Used as a specific ligand in receptor binding studies and other in vitro diagnostic applications.
• Academic Research: Serves as a critical tool for studying reproductive endocrinology and neuropeptide signaling pathways.
• API Development: Potential use as an active pharmaceutical ingredient (API) in the formulation of specialty injectables.

Basic Information

Product Name	Prazarelix
CAS No.	134457-28-6
Molecular Formula	C₆₀H₈₈N₁₈O₁₃
Molecular Weight	1269.5 g/mol
Synonyms	Prazarelix; Azaline B; (Ac-D-Nal-D-Cpa-D-Pal-Ser-N-MeTyr-D-Asn-Leu-Lys(iPr)-Pro-D-Ala-NH₂); GnRH Antagonist (Azaline B); FE 200486; FE200486; Azaline-B; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-N-methyl-L-tyrosyl-D-asparaginyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-D-alaninamide
EINECS	Contact for details

Quality Control

Our Prazarelix is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under desiccant or inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.