Description

Lhrh, n-Ac-Nal(1)-4-Cl-Phe(2)-Trp(3)-Cit(6)-Alanh2(10)- CAS NO 120287-84-5 is a synthetic peptide analog of luteinizing hormone-releasing hormone (LHRH) with specific amino acid substitutions designed to modulate biological activity. This compound is of significant value for advanced research and development in endocrinology and oncology, serving as a critical tool for studying hormone-receptor interactions. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on developing novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active pharmaceutical ingredient (API) in the development of novel hormone-based therapies.
• Endocrinology Studies: A key tool for investigating the structure-activity relationships (SAR) of LHRH analogs and their effects on the hypothalamic-pituitary-gonadal axis.
• Oncology Research: Investigated for potential applications in targeted cancer treatments, particularly for hormone-sensitive cancers such as prostate and breast cancer.
• Biochemical Assay Development: Employed in the development and validation of high-throughput screening (HTS) assays and diagnostic kits.
• Peptide Chemistry & Synthesis: Serves as a complex intermediate or final product for studying advanced peptide synthesis and modification techniques.
• Academic & Institutional Research: Utilized in university and government labs for fundamental research in reproductive biology and signal transduction.

Basic Information

Item	Details
Product Name	Lhrh, n-Ac-Nal(1)-4-Cl-Phe(2)-Trp(3)-Cit(6)-Alanh2(10)- CAS NO 120287-84-5
CAS No.	120287-84-5
Molecular Formula	C64H83N17O12Cl
Molecular Weight	1269.9 g/mol
Synonyms	Ac-D-Nal(1)-4-Cl-D-Phe(2)-D-Trp(3)-D-Arg(6)-LH-RH; LHRH Antagonist (Ac-D-Nal-4-Cl-D-Phe-D-Trp-D-Arg); [Ac-D-Nal1,4-Cl-D-Phe2,D-Trp3,D-Arg6]-LHRH; GnRH Antagonist Analog; Gonadotropin-Releasing Hormone Antagonist; Luteinizing Hormone-Releasing Hormone Analog; Synthetic Decapeptide Analog; 120287-84-5
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing parameters such as purity, identity, and impurity profiles. We adhere to GMP (Good Manufacturing Practice) guidelines for the handling of advanced pharmaceutical intermediates, ensuring traceability and consistency for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain purity and prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in DMSO, Acetic Acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.