Description

Triptorelin (Free Acid) CAS NO 129418-54-8 is a synthetic decapeptide analog of gonadotropin-releasing hormone (GnRH). This compound is a critical active pharmaceutical ingredient (API) and a key intermediate in the synthesis of various therapeutic formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of advanced hormone therapies. The product's high purity and stability are essential for ensuring the efficacy and safety of the final drug products.

Application

• Pharmaceutical API Synthesis: Primary use as the active ingredient in the manufacture of long-acting GnRH agonist formulations.
• Oncology Therapeutics: Used in the production of drugs for the treatment of hormone-sensitive cancers, such as prostate cancer and certain breast cancers.
• Endocrinology Treatments: Key component in medications for central precocious puberty (CPP) and other endocrine disorders.
• Veterinary Medicine: Employed in veterinary pharmaceuticals for reproductive control and treatment of hormone-dependent conditions in animals.
• Biomedical Research: Serves as a reference standard and critical reagent in biochemical and pharmacological studies of the hypothalamic-pituitary-gonadal axis.
• Peptide Chemistry Development: Used as a high-purity building block for the research and development of novel peptide-based therapeutics.

Basic Information

Item	Detail
Product Name	Triptorelin (Free Acid)
CAS No.	129418-54-8
Molecular Formula	C₆₄H₈₂N₁₈O₁₃
Molecular Weight	1311.5 g/mol
Synonyms	Triptorelin; Triptorelin Free Acid; Gonadorelin (6-D-tryptophan) analog; PGL-0137; Decapeptyl (Free Acid); 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolylglycinamide; Gonadotropin-Releasing Hormone Agonist (6-D-Trp); (6-D-Trp)-LHRH
EINECS	Contact for details

Quality Control

Our Triptorelin (Free Acid) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, residual solvent analysis, and identification by mass spectrometry and NMR, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0% (Total Peptide Content)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.