Description

Ganirelix Acetate is a synthetic decapeptide that acts as a potent gonadotropin-releasing hormone (GnRH) antagonist. This compound is critical for the controlled inhibition of gonadotropin secretion in therapeutic protocols. It is primarily utilized in the pharmaceutical and biotechnology sectors for advanced reproductive medicine and clinical research applications.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active component in injectable formulations for fertility control.
• Assisted Reproductive Technology (ART): Used in in vitro fertilization (IVF) cycles to prevent premature luteinizing hormone (LH) surges.
• Clinical Research: Serves as a key reference standard and investigational agent in endocrinology and reproductive health studies.
• Drug Development: Employed in preclinical and formulation research for new therapeutic entities targeting hormone-dependent conditions.
• Biochemical Research: Used as a specific GnRH receptor antagonist in pharmacological and signal transduction studies.

Basic Information

Product Name	Ganirelix Acetate
CAS No.	123246-29-7
Molecular Formula	C₈₀H₁₀₃ClN₁₈O₁₃ • xC₂H₄O₂
Molecular Weight	1570.3 g/mol (base)
Synonyms	Ganirelix; Antagon; Ganirelix Acetate Salt; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-N6-(N-ethyl-L-α-asparaginyl)-4,4-difluoro-L-lysyl-N6-(N-ethyl-L-α-asparaginyl)-L-leucyl-N6-(N-ethyl-L-α-asparaginyl)-L-prolyl-D-alaninamide Acetate; D-63153; GnRH Antagonist (Ganirelix)
EINECS	Contact for details

Quality Control

Our Ganirelix Acetate is manufactured under strict quality systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical development and research use. A comprehensive Certificate of Analysis (COA) is provided, detailing results for identity, purity, and related substances as per validated methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Acetate Content (IC)	5.0% - 12.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.