Description

Cetrorelix Acetate is a synthetic decapeptide and a potent gonadotropin-releasing hormone (GnRH) antagonist. This compound is critical for the controlled inhibition of gonadotropin secretion, offering a high degree of specificity and efficacy. It is primarily utilized in advanced pharmaceutical research and development, as well as in clinical applications within reproductive medicine and oncology. Our supply ensures the high purity and consistency required for these sensitive applications.

Application

• Pharmaceutical Active Ingredient (API): Core component in injectable formulations for fertility control and assisted reproductive technologies (ART).
• Clinical Research: Used in studies for the treatment of hormone-dependent conditions such as prostate cancer, endometriosis, and uterine fibroids.
• Biochemical Research: Serves as a reference standard and a critical tool in endocrinology and peptide hormone interaction studies.
• Drug Development: Employed in preclinical and formulation development for novel GnRH antagonist-based therapies.

Basic Information

Product Name	Cetrorelix Acetate
CAS No.	130143-01-0
Molecular Formula	C₇₀H₉₂ClN₁₇O₁₄ • xC₂H₄O₂
Molecular Weight	1431.0 g/mol (free base)
Synonyms	Cetrorelix; Cetrotide; Ac-D-Nal-D-Cpa-D-Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH₂ acetate; (Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(carbamoyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide acetate); Azaline B; GnRH Antagonist (Cetrorelix); D-20761
EINECS	Contact for details

Quality Control

Our Cetrorelix Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, peptide mapping, and residual solvent analysis, to ensure it meets stringent standards suitable for pharmaceutical research. A Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature or as specified on the label. Due to its hygroscopic nature, the product should be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 8.0%
Acetate Content (IC)	5.0% - 12.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.