Description

Neocarzinostatin is a potent proteinaceous antitumor antibiotic isolated from *Streptomyces carzinostaticus*. This compound is of significant interest in biochemical and pharmaceutical research due to its unique mechanism of action, which involves DNA strand scission. It is primarily utilized by research institutions and pharmaceutical developers focused on oncology, molecular biology, and the study of novel therapeutic agents.

Application

• Oncology Research: A key tool for studying DNA damage mechanisms and apoptosis in cancer cell lines.
• Biochemical Studies: Used to investigate protein-DNA interactions and the biochemistry of enediyne antibiotics.
• Pharmaceutical Development: Serves as a reference standard and a lead compound in the development of new anticancer therapies.
• Academic Research: Employed in university and institutional labs for fundamental research in molecular genetics and cell biology.

Basic Information

Product Name	Neocarzinostatin
CAS No.	9014-02-2
Molecular Formula	C107H138N24O31S2
Molecular Weight	~ 2300 g/mol (Protein component)
Synonyms	NCS; Neocarzinostatin; Zinostatin; NSC 698666; Antibiotic NSC 698666; Antitumor antibiotic NSC 698666; Carzinostatin; Landomycin A; SMANCS (Styrene Maleic Acid Neocarzinostatin Conjugate)
EINECS	Contact for details

Quality Control

Our Neocarzinostatin is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for research purposes. Each lot is characterized for identity and biological activity. A comprehensive Certificate of Analysis (COA), detailing purity, potency, and other critical parameters, is provided to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This material is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep desiccated under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Biological Activity (Cell-based assay)	Reported per batch
Water Content (KF)	≤ 5.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.