Description

Cyproheptadine Hydrochloride is a first-generation antihistamine and serotonin antagonist with significant pharmacological activity. This compound is a critical active pharmaceutical ingredient (API) valued for its precise chemical structure and reliable biological effects. It is primarily required by pharmaceutical manufacturers for the formulation of prescription medications targeting allergic conditions and appetite stimulation.

Application

• Pharmaceutical API: Core ingredient in the manufacture of antihistamine tablets and syrups.
• Allergy Medication: Used in formulations to treat symptoms of allergic rhinitis, conjunctivitis, and chronic urticaria.
• Appetite Stimulant: Employed in therapeutic products to promote weight gain in underweight patients.
• Migraine Prophylaxis: Component in some preventive treatments for vascular headaches and migraine disorders.
• Veterinary Pharmaceuticals: Used in animal health products for allergic and dermatological conditions.
• Research & Development: Serves as a reference standard and building block in pharmacological and biochemical research.

Basic Information

Product Name	Cyproheptadine Hydrochloride
CAS No.	969-33-5
Molecular Formula	C21H21N·HCl
Molecular Weight	323.86 g/mol
Synonyms	Periacin; Periactin; Cyproheptadine HCl; 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine hydrochloride; MK-141; (1-Methyl-4-(5-dibenzo[a,e]cycloheptatrienylidene))piperidine hydrochloride; N-methyl-4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)piperidine hydrochloride
EINECS	213-527-5

Quality Control

Our Cyproheptadine Hydrochloride is manufactured under strict quality management systems. It undergoes comprehensive analytical testing to meet high-purity standards suitable for pharmaceutical applications, including identification, assay, and impurity profile analysis. A Certificate of Analysis (COA) confirming compliance with in-house specifications is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.