Description

9,11β-Epoxy-17-Hydroxy-16β-Methyl-3,20-Dioxo-9β-Pregna-1,4-Diene-21-Yl Acetate CAS NO 912-38-9 is a high-purity steroid derivative and a key synthetic intermediate in advanced pharmaceutical manufacturing. Its complex molecular structure is engineered to serve as a crucial precursor in the synthesis of potent corticosteroid APIs, enabling precise control over biological activity and metabolic pathways. This compound is essential for R&D and production teams in the pharmaceutical and fine chemical sectors focused on developing next-generation anti-inflammatory and immunosuppressive therapies.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of advanced corticosteroid active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and structural modification of new steroidal drug candidates.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for high-value steroid products.
• Reference Standard: Serves as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	9,11β-Epoxy-17-Hydroxy-16β-Methyl-3,20-Dioxo-9β-Pregna-1,4-Diene-21-Yl Acetate
CAS No.	912-38-9
Molecular Formula	C₂₄H₃₀O₆
Molecular Weight	414.50 g/mol
Synonyms	9β,11β-Epoxy-17α-hydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-acetate; 21-Acetoxy-9β,11β-epoxy-17α-hydroxy-16β-methylpregna-1,4-diene-3,20-dione; 16β-Methyl-9β,11β-epoxyprednisolone 21-acetate; Betamethasone 9,11-Epoxide 21-Acetate; (9β,11β,16β)-9,11-Epoxy-17-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate; NSC 119185
EINECS	Contact for details

Quality Control

Our 9,11β-Epoxy-17-Hydroxy-16β-Methyl-3,20-Dioxo-9β-Pregna-1,4-Diene-21-Yl Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are kept sealed in a dry environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.