Description

17,21-Dihydroxy-16Beta-Methylpregna-1,4,9(11)-Triene-3,20-Dione 21-Acetate is a high-purity steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical key intermediate for the synthesis of more complex therapeutic agents, particularly within the corticosteroid class. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel anti-inflammatory and immunosuppressive drugs.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent corticosteroid APIs (Active Pharmaceutical Ingredients).
• Research Chemical: Used in academic and industrial laboratories for studying steroid metabolism, receptor binding, and structure-activity relationships (SAR).
• Process Development: Serves as a reference standard and starting material for optimizing scalable manufacturing routes for steroid-based therapeutics.
• Fine Chemical Synthesis: Employed in the custom synthesis of specialized steroid analogs for preclinical and clinical investigation.

Basic Information

Product Name	17,21-Dihydroxy-16Beta-Methylpregna-1,4,9(11)-Triene-3,20-Dione 21-Acetate
CAS No.	910-99-6
Molecular Formula	C24H30O5
Molecular Weight	398.50 g/mol
Synonyms	16β-Methylprednisolone 21-Acetate; 16β-Methyl-1,4,9(11)-pregnatriene-17α,21-diol-3,20-dione 21-acetate; 16β-Methylprednisolone acetate; 9(11)-Dehydro-16β-methylprednisolone 21-acetate; 16β-Methyl-δ1,4,9(11)-pregnatriene-17α,21-diol-3,20-dione 21-acetate; NSC 47439; 16β-Methyl-9(11)-dehydroprednisolone 21-acetate
EINECS	Contact for details

Quality Control

Our 17,21-Dihydroxy-16Beta-Methylpregna-1,4,9(11)-Triene-3,20-Dione 21-Acetate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.