Description

Pregn-4-Ene-3,20-Dione, 11.Beta.,16.Alpha.,17,21-Tetrahydroxy-16-Methyl- is a high-purity synthetic corticosteroid intermediate of significant commercial and research importance. This compound serves as a critical building block in the pharmaceutical synthesis of potent anti-inflammatory and immunosuppressive agents. It is essential for manufacturers and R&D facilities in the steroid hormone and active pharmaceutical ingredient (API) sectors seeking reliable, high-quality raw materials for advanced drug development and production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of advanced corticosteroid drugs, including methylprednisolone and related analogs.
• Anti-inflammatory Agent R&D: Used in research and development of new therapeutic compounds targeting inflammation and autoimmune disorders.
• Steroid Hormone Manufacturing: A vital raw material for the production of complex steroid-based Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Employed in laboratory studies to investigate glucocorticoid receptor activity and metabolic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical laboratories.

Basic Information

Product Name	Pregn-4-Ene-3,20-Dione, 11.Beta.,16.Alpha.,17,21-Tetrahydroxy-16-Methyl-
CAS No.	910-20-3
Molecular Formula	C22H32O6
Molecular Weight	392.49 g/mol
Synonyms	16α-Methylprednisolone; 11β,16α,17,21-Tetrahydroxy-16α-methylpregn-4-ene-3,20-dione; 16α-Methyl-11β,17α,21-trihydroxypregn-4-ene-3,20-dione; 16α-Methyl-δ1-cortisol; NSC 527579; Medrol Intermediate; Methylprednisolone Intermediate A
EINECS	Contact for details

Quality Control

Our Pregn-4-Ene-3,20-Dione, 11.Beta.,16.Alpha.,17,21-Tetrahydroxy-16-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards suitable for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.