Description

Pyrilamine CAS NO 91-84-9 is an organic compound belonging to the ethylenediamine class of H1-antihistamines. This versatile active pharmaceutical ingredient (API) is valued for its potent antihistaminic properties, effectively blocking histamine H1 receptors to alleviate allergic symptoms. It is a critical raw material for manufacturers in the pharmaceutical and life sciences sectors, particularly for formulating antihistamine medications, topical creams, and certain veterinary products.

Application

• Primary active ingredient in antihistamine pharmaceutical formulations for treating allergies, hay fever, and urticaria.
• Key component in over-the-counter (OTC) cold and flu medications, often combined with analgesics and decongestants.
• Used in the development of topical creams and ointments for skin allergies and insect bite relief.
• Intermediate in veterinary pharmaceuticals for allergic conditions in animals.
• Reference standard in analytical and quality control laboratories for method development and validation.
• Starting material or intermediate for chemical synthesis of related pharmaceutical compounds.
• Used in research and development within pharmacological studies of histamine receptors.

Basic Information

Product Name	Pyrilamine
CAS No.	91-84-9
Molecular Formula	C17H23N3O
Molecular Weight	285.39 g/mol
Synonyms	Mepyramine; Pyrilamine Maleate (salt form); Anthisan; Histadyl; Neo-Antergan; N-(4-Methoxybenzyl)-N',N'-dimethyl-N-2-pyridylethylenediamine; 2-[(2-Dimethylaminoethyl)(4-methoxybenzyl)amino]pyridine; N-(p-Methoxybenzyl)-N',N'-dimethyl-N-α-pyrid-2-ylethylenediamine
EINECS	202-101-1

Quality Control

Our Pyrilamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.