Description

Tripelennamine is a first-generation ethylenediamine-class H1-antihistamine compound, recognized for its potent and selective antagonism of histamine receptors. This makes it a valuable active pharmaceutical ingredient (API) and a key intermediate in the synthesis of more complex therapeutic agents. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development and production of antihistamine medications, allergy treatments, and for investigative purposes in pharmacological studies.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of antihistamine tablets, creams, and injectables for treating allergic conditions.
• Chemical Intermediate: Serves as a critical building block in the organic synthesis of novel pharmaceutical compounds and more advanced antihistamine derivatives.
• Research & Development: Used in biochemical and pharmacological research to study histamine pathways, receptor binding, and the mechanisms of allergic responses.
• Veterinary Medicine: Employed in the development of antihistamine treatments for allergic reactions and dermatological conditions in animals.
• Reference Standard: Sourced by analytical laboratories for use as a high-purity standard in quality control (QC) and assay development for pharmaceutical products.

Basic Information

Product Name	Tripelennamine
CAS No.	91-81-6
Molecular Formula	C16H21N3
Molecular Weight	255.36 g/mol
Synonyms	Pyribenzamine; PBZ; N-Benzyl-N',N'-dimethyl-N-2-pyridylethylenediamine; 2-[(Benzyl)(2-dimethylaminoethyl)amino]pyridine; Tripeleannamine; Tripelenamine; Tripelennaminum
EINECS	202-101-5

Quality Control

Our Tripelennamine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting specifications suitable for pharmaceutical research and development. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.