Description

Methapyrilene CAS NO 91-80-5 is a chemical compound belonging to the ethylenediamine class of antihistamines. This substance is of significant interest in research and development, particularly for its historical pharmacological profile and its utility as a reference standard. It is primarily sought by organizations in the pharmaceutical, analytical, and life science sectors for use in method development, quality control, and investigative studies.

Application

• Pharmaceutical research and development as a reference compound.
• Analytical chemistry as a high-purity standard for method validation and calibration.
• Use in laboratory studies investigating the metabolism and pharmacokinetics of antihistaminic agents.
• Chemical synthesis as a building block or intermediate for specialized derivatives.
• Quality control (QC) and quality assurance (QA) in pharmaceutical manufacturing environments.
• Academic and institutional research in pharmacology and medicinal chemistry.

Basic Information

Product Name	Methapyrilene
CAS No.	91-80-5
Molecular Formula	C14H19N3S
Molecular Weight	261.39 g/mol
Synonyms	Methapyrilene Hydrochloride (common salt form); N,N-Dimethyl-N'-pyrid-2-yl-N'-thien-2-ylethylenediamine; Thenylpyramine; Histadyl; Thenylene; Semikon; Dormin; 2-[(2-Dimethylaminoethyl)(2-pyridyl)amino]pyridine; 1,2-Ethanediamine, N,N-dimethyl-N'-2-pyridinyl-N'-2-thienyl-
EINECS	202-099-5

Quality Control

Our Methapyrilene is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA) upon request, which include data from advanced techniques such as HPLC, NMR, and mass spectrometry to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.