Description

Antazoline is a potent and selective antihistamine compound belonging to the ethylenediamine class. This active pharmaceutical ingredient (API) is valued for its efficacy in blocking H1 histamine receptors, providing rapid relief from allergic symptoms. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of ophthalmic and nasal solutions for allergy relief, as well as in various preclinical studies.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription and over-the-counter (OTC) ophthalmic solutions and nasal sprays for the treatment of allergic conjunctivitis and rhinitis.
• Veterinary Medicine: Formulation into topical preparations for managing allergic reactions and irritations in animals.
• Biochemical Research: Serves as a critical reference standard and pharmacological tool in studies of histamine receptor function and mechanism of action.
• Drug Development: Used in the synthesis and development of new antihistamine derivatives and combination therapies.

Basic Information

Product Name	Antazoline
CAS No.	91-75-8
Molecular Formula	C17H19N3
Molecular Weight	265.35 g/mol
Synonyms	Antazoline; 2-[(N-Benzylanilino)methyl]-2-imidazoline; Antasten; Antistin; Phenazoline; N-(Benzylanilino)methylimidazoline; Imidamine; 2-[(N-Benzyl-N-phenylamino)methyl]-2-imidazoline
EINECS	202-095-9

Quality Control

Our Antazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specifications for identity, purity, and impurities. We support compliance with major pharmacopoeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.