Description

3-Fluoro-4-Methoxybenzoylacetonitrile is a versatile fluorinated aromatic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Chemical Biology Probes: Employed in the design of fluorinated probes and tags for studying biological processes and enzyme mechanisms.
• Advanced Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored thermal and optical properties.
• Academic & Contract Research: A valuable reagent for method development and exploration of new fluorination and cyanoacetylation reactions in academic and CRO settings.

Basic Information

Product Name	3-Fluoro-4-Methoxybenzoylacetonitrile
CAS No.	898786-96-4
Molecular Formula	C10H8FNO2
Molecular Weight	193.17 g/mol
Synonyms	3-Fluoro-4-methoxybenzoylacetonitrile; 4-Methoxy-3-fluorobenzoylacetonitrile; 1-(3-Fluoro-4-methoxyphenyl)-2-cyanoethanone; 2-Cyano-1-(3-fluoro-4-methoxyphenyl)ethanone; 3-Fluoro-4-methoxy-ω-cyanacetophenone; (3-Fluoro-4-methoxyphenyl)(cyano)methanone; 898786-96-4; 3-Fluoro-p-anisoylacetonitrile
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methoxybenzoylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects requiring compliance with ICH guidelines and cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.