Description

3',5'-Difluoro-3-(4-Methylphenyl)Propiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise chemical scaffold to facilitate the synthesis of novel drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug molecules, particularly those requiring a difluorinated phenyl ketone moiety.
• Agrochemical Research: Used in the development and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and stability.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals, contributing to unique optical and electronic properties.
• Organic Synthesis: Employed in cross-coupling reactions, such as Suzuki or Heck reactions, to create complex aromatic systems for research and development.
• Fluorine Chemistry Studies: A valuable substrate for investigating the effects of fluorine substitution on chemical reactivity and physical properties.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3',5'-Difluoro-3-(4-Methylphenyl)Propiophenone
CAS No.	898769-40-9
Molecular Formula	C16H14F2O
Molecular Weight	260.28 g/mol
Synonyms	1-(3,5-Difluorophenyl)-3-(p-tolyl)propan-1-one; 3-(4-Methylphenyl)-1-(3,5-difluorophenyl)propan-1-one; 3',5'-Difluoro-3-(p-tolyl)propiophenone; 3,5-Difluoro-3'-(4-methylphenyl)propiophenone; 898769-40-9; Propiophenone, 3',5'-difluoro-3-(4-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 3',5'-Difluoro-3-(4-Methylphenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for pharmaceutical and advanced research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.