Description

6-(3-Fluorophenyl)-6-Oxohexanenitrile is a specialized organic building block featuring a fluorinated aromatic ketone moiety linked to a nitrile-terminated alkyl chain. This unique bifunctional structure makes it a valuable intermediate for synthesizing more complex molecules in advanced research and development. It is primarily sought by pharmaceutical and agrochemical R&D teams for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or insecticides where the fluorophenyl group can enhance biological activity and stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for creating fluorinated aromatic cores in advanced electronic and display materials.
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymer backbones, potentially altering thermal stability and solubility properties.
• Chemical Biology Probes: Useful for creating fluorescent tags or affinity probes due to its reactive ketone and nitrile functional groups.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific fluorinated aromatic architectures.

Basic Information

Product Name	6-(3-Fluorophenyl)-6-Oxohexanenitrile
CAS No.	898767-21-0
Molecular Formula	C₁₂H₁₂FNO
Molecular Weight	205.23 g/mol
Synonyms	6-Oxo-6-(3-fluorophenyl)hexanenitrile; 3-Fluorobenzoylvaleronitrile; 6-(3-Fluorobenzoyl)hexanenitrile; 5-Cyano-1-(3-fluorophenyl)-1-pentanone; 1-(3-Fluorophenyl)-5-cyanopentan-1-one; γ-Cyano-γ-oxo-3-fluorophenylbutane; 898767-21-0
EINECS	Contact for details

Quality Control

Every batch of 6-(3-Fluorophenyl)-6-Oxohexanenitrile is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.