Description

Ethyl 6-(2-Fluorophenyl)-6-Oxohexanoate is a high-purity fluorinated ketoester building block designed for advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of complex pharmaceutical and agrochemical molecules. It is primarily sought by research and development chemists, process development scientists, and manufacturers in the fine chemical and pharmaceutical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, where the fluorine atom and ketoester functionality can enhance biological activity and stability.
• Material Science Precursor: Serves as a monomer or building block for specialty polymers and liquid crystals, leveraging its aromatic and ester groups.
• Chemical Synthesis: Employed in multi-step organic reactions, including Grignard additions, reductions, and cyclizations, to create complex molecular architectures.
• Academic & Industrial R&D: Utilized in research laboratories for methodological studies and the discovery of new chemical entities (NCEs).

Basic Information

Product Name	Ethyl 6-(2-Fluorophenyl)-6-Oxohexanoate
CAS No.	898753-38-3
Molecular Formula	C14H17FO3
Molecular Weight	252.28 g/mol
Synonyms	6-Oxo-6-(2-fluorophenyl)hexanoic acid ethyl ester; Ethyl 6-oxo-6-(2-fluorophenyl)hexanoate; 2-Fluorobenzoylbutyric acid ethyl ester; 6-(2-Fluorobenzoyl)hexanoic acid ethyl ester; Ethyl 6-(2-fluorobenzoyl)hexanoate; Hexanoic acid, 6-(2-fluorophenyl)-6-oxo-, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 6-(2-Fluorophenyl)-6-Oxohexanoate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay, related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to fluoride/strong alkali and high volatility, keep away from incompatible materials and ensure containers are securely sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.