Description

3-Fluoro-2-(trifluoromethyl)pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group on the pyridine ring, is engineered to impart enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with improved performance profiles.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of modern pesticides and herbicides, where the fluorine atoms contribute to increased efficacy and environmental persistence.
• Material Science: Acts as a precursor for specialty chemicals, including liquid crystals, organic light-emitting diodes (OLEDs), and advanced polymers.
• Chemical Research: Serves as a versatile reagent in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fluorination Chemistry: Employed as a stable source of a fluorinated heterocyclic scaffold in cross-coupling reactions and other metal-catalyzed transformations.

Basic Information

Product Name	3-Fluoro-2-(trifluoromethyl)pyridine
CAS No.	897940-14-6
Molecular Formula	C6H3F4N
Molecular Weight	165.09 g/mol
Synonyms	2-(Trifluoromethyl)-3-fluoropyridine; 3-Fluoro-2-trifluoromethylpyridine; 3-Fluoro-2-(trifluoromethyl)pyridine; Pyridine, 3-fluoro-2-(trifluoromethyl)-; 3-Fluoro-2-(trifluoromethyl)Ph (abbrev.); 3-F-2-TFMP
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-(trifluoromethyl)pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistency suitable for demanding R&D and scale-up applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.