Description

3-[3-(Trifluoromethyl)Phenyl]Benzonitrile is a high-purity fluorinated aromatic nitrile building block. This compound is valued for its unique trifluoromethylphenyl moiety, which imparts enhanced lipophilicity and metabolic stability to target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in areas targeting CNS disorders and inflammation.
• Agrochemical Research: Used in the synthesis of novel herbicides and fungicides, leveraging the bioactivity of the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic display and lighting technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce the biaryl nitrile scaffold into more complex molecular architectures.
• Chemical Biology Probe Development: Used as a tagged molecular fragment in the discovery of enzyme inhibitors and receptor modulators.

Basic Information

Product Name	3-[3-(Trifluoromethyl)Phenyl]Benzonitrile
CAS No.	893734-87-7
Molecular Formula	C14H8F3N
Molecular Weight	247.22 g/mol
Synonyms	[3-(3-Trifluoromethylphenyl)phenyl]acetonitrile; 3'-(Trifluoromethyl)[1,1'-biphenyl]-3-carbonitrile; 3-(3-Trifluoromethylphenyl)benzonitrile; m-(Trifluoromethyl)m-terphenyl-3'-carbonitrile; 3-Cyano-3'-(trifluoromethyl)biphenyl; Biphenyl-3-carbonitrile, 3'-(trifluoromethyl)-; 3-(3-(Trifluoromethyl)phenyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 3-[3-(Trifluoromethyl)Phenyl]Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.