Description

3-(3-Fluorophenyl)Benzonitrile is a high-purity fluorinated aromatic nitrile building block, essential for advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and functional agrochemicals where the introduction of a fluorine atom and a nitrile group is critical.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially in kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides where fluorinated aromatic structures enhance biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed as a building block for electron-transport or host materials in OLED device fabrication.
• Cross-Coupling Reactions: Utilized in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to construct biaryl systems.
• Material Science Research: Acts as a monomer or modifier in the synthesis of specialized polymers and advanced organic frameworks.

Basic Information

Product Name	3-(3-Fluorophenyl)Benzonitrile
CAS No.	893734-83-3
Molecular Formula	C13H8FN
Molecular Weight	197.21 g/mol
Synonyms	3'-Fluoro-[1,1'-biphenyl]-3-carbonitrile; [1,1'-Biphenyl]-3-carbonitrile, 3'-fluoro-; 3-(3-Fluorophenyl)benzonitrile; 3-Fluoro-3'-cyanobiphenyl; m-Fluorophenyl benzonitrile
EINECS	Contact for details

Quality Control

Our 3-(3-Fluorophenyl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.