Description

3'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Carbonitrile is a high-purity biphenyl derivative featuring a trifluoromethyl group and a nitrile functional group, making it a versatile and valuable synthetic intermediate. Its molecular structure is engineered to serve as a critical building block in advanced organic synthesis, particularly for introducing specific fluorinated aromatic motifs. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require reliable, high-quality intermediates for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated compounds for electronic displays and optical devices.
• Organic Light-Emitting Diodes (OLEDs): Acts as a core structure for developing electron-transport or host materials in OLED fabrication.
• Material Science Research: Employed in academic and industrial R&D to create novel polymers and advanced organic materials with specific electronic properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.

Basic Information

Product Name	3'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Carbonitrile
CAS No.	893734-56-0
Molecular Formula	C14H8F3N
Molecular Weight	247.22 g/mol
Synonyms	4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carbonitrile; [1,1'-Biphenyl]-4-carbonitrile, 3'-(trifluoromethyl)-; 3'-(Trifluoromethyl)biphenyl-4-carbonitrile; 4-Cyano-3'-(trifluoromethyl)biphenyl; 3-Trifluoromethyl-4-cyanobiphenyl; 4-Cyano-4'-(trifluoromethyl)biphenyl; 3'-Trifluoromethyl-4-cyanobiphenyl
EINECS	Contact for details

Quality Control

Our 3'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The container must be kept tightly sealed due to the compound's sensitivity to moisture (hygroscopic).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.