Description

3'-Fluoro[1,1'-Biphenyl]-4-Carbonitrile is a high-purity fluorinated biphenyl derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the precise molecular architecture that combines a fluorine substituent with a nitrile group, enabling fine-tuning of electronic properties and serving as a versatile synthetic intermediate. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a core structure in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved performance and stability.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Negishi) and cyano group transformations to construct complex polycyclic aromatic systems for material science.
• Chemical Reference Standard: Employed as an analytical standard in quality control and method development for pharmaceutical and chemical analysis.

Basic Information

Product Name	3'-Fluoro[1,1'-Biphenyl]-4-Carbonitrile
CAS No.	893734-52-6
Molecular Formula	C₁₃H₈FN
Molecular Weight	197.21 g/mol
Synonyms	4-Cyano-3'-fluorobiphenyl; [1,1'-Biphenyl]-4-carbonitrile, 3'-fluoro-; 3'-Fluoro-4-cyanobiphenyl; 3-Fluorobiphenyl-4-carbonitrile; 3'-Fluoro-4-biphenylcarbonitrile; 3-Fluoro-4-phenylbenzonitrile; 4-(3-Fluorophenyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 3'-Fluoro[1,1'-Biphenyl]-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.