Description

Benzonitrile, 4-Bromo-2-Fluoro-5-Nitro- CAS NO 893615-25-3 is a high-purity, multi-substituted aromatic nitrile building block of significant importance in advanced organic synthesis. Its unique halogenated and nitro-functionalized structure makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the bromo, fluoro, and nitro groups contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile building block for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers where its electron-withdrawing groups fine-tune material properties.
• Chemical Biology Probes: Utilized to create fluorescent tags, photoaffinity labels, and other molecular probes for studying biological systems and drug-target interactions.
• Custom Synthesis and R&D: A valuable starting material for contract research organizations (CROs) and academic laboratories engaged in medicinal chemistry and novel compound library development.

Basic Information

Product Name	Benzonitrile, 4-Bromo-2-Fluoro-5-Nitro-
CAS No.	893615-25-3
Molecular Formula	C7H2BrFN2O2
Molecular Weight	244.99 g/mol
Synonyms	4-Bromo-2-fluoro-5-nitrobenzonitrile; 2-Fluoro-4-bromo-5-nitrobenzonitrile; 5-Nitro-4-bromo-2-fluorobenzonitrile; Benzonitrile, 4-bromo-2-fluoro-5-nitro-; 4-Bromo-2-fluoro-5-nitro-benzonitrile; 893615-25-3; 4-Br-2-F-5-NO2-Bn
EINECS	Contact for details

Quality Control

Our Benzonitrile, 4-Bromo-2-Fluoro-5-Nitro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity building blocks for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.