Description

1-Bromo-4-Fluoro-2-Nitro-5-(Trifluoromethyl)Benzene is a high-value, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring bromo, fluoro, nitro, and trifluoromethyl substituents, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and electronic materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to construct complex, poly-substituted benzene derivatives.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	1-Bromo-4-Fluoro-2-Nitro-5-(Trifluoromethyl)Benzene
CAS No.	889459-13-6
Molecular Formula	C7H2BrF4NO2
Molecular Weight	288.00 g/mol
Synonyms	2-Bromo-5-fluoro-4-nitrobenzotrifluoride; 4-Bromo-1-fluoro-2-nitro-5-(trifluoromethyl)benzene; 5-Bromo-2-fluoro-4-nitrobenzotrifluoride; 1-Bromo-4-fluoro-2-nitro-5-(trifluoromethyl)benzene; Benzene, 1-bromo-4-fluoro-2-nitro-5-(trifluoromethyl)-; 889459-13-6; BCP32563
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Fluoro-2-Nitro-5-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.