Description

3-Chloro-2,4-Difluorobenzonitrile is a high-purity, multi-functional aromatic nitrile building block distinguished by its strategic halogen substitution pattern. This compound is engineered to serve as a critical intermediate in advanced organic synthesis, enabling the development of complex molecules with tailored properties. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for constructing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates where its structure imparts metabolic stability and modulates lipophilicity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the chloro and difluoro substituents to enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, where its electronic properties are crucial for performance.
• Polymer & Resin Modifier: Incorporated as a monomer or cross-linking agent to create specialty polymers with enhanced chemical resistance, thermal stability, and specific surface properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring novel heterocyclic chemistry, coupling reactions, and as a scaffold in medicinal chemistry programs.

Basic Information

Product Name	3-Chloro-2,4-Difluorobenzonitrile
CAS No.	887267-38-1
Molecular Formula	C7H2ClF2N
Molecular Weight	173.55 g/mol
Synonyms	2,4-Difluoro-3-chlorobenzonitrile; 3-Chloro-2,4-difluorobenzene carbonitrile; Benzonitrile, 3-chloro-2,4-difluoro-; 3-Chloro-2,4-difluorophenyl cyanide
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,4-Difluorobenzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency meet the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.