Description

1-Fluoro-3-Iodo-2-Nitrobenzene is a halogenated nitroaromatic compound of significant interest in advanced organic synthesis. This multi-functional intermediate is valued for its unique reactivity profile, enabling precise molecular construction in complex chemical environments. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for building novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogen and nitro groups for bioactivity.
• Material Science Research: Serves as a precursor for functionalized organic materials, including liquid crystals, organic semiconductors, and photoactive polymers.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira, Stille couplings) due to the reactive iodine atom.
• Nucleophilic Aromatic Substitution: The activated nitro and fluoro groups make it suitable for substitution reactions to introduce diverse functional groups.
• Chemical Biology Probes: Used in the development of molecular probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	1-Fluoro-3-Iodo-2-Nitrobenzene
CAS No.	886762-71-6
Molecular Formula	C6H3FINO2
Molecular Weight	266.99 g/mol
Synonyms	2-Nitro-1-fluoro-3-iodobenzene; 3-Iodo-2-nitrofluorobenzene; 1-Fluoro-3-iodo-2-nitrobenzene; 2-Fluoro-6-iodonitrobenzene; Benzene, 1-fluoro-3-iodo-2-nitro-; (3-Iodo-2-nitrophenyl) fluoride
EINECS	Contact for details

Quality Control

Our 1-Fluoro-3-Iodo-2-Nitrobenzene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems support compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, minimize exposure during handling.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.