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2-Bromo-6-Fluoronitrobenzene CAS NO 886762-70-5


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CAS No.:886762-70-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Bromo-6-Fluoronitrobenzene is a high-purity halogenated nitrobenzene derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents ortho to a nitro group, makes it a versatile precursor for constructing complex molecules where regioselective functionalization is paramount. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

  • Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in the synthesis of fluorinated heterocycles and complex aromatic systems.
  • Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
  • Material Science Research: Serves as a monomer or precursor for the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
  • Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig aminations, enabling C-C and C-N bond formation.
  • Fluorine Chemistry Studies: Utilized in research to study the electronic effects and reactivity patterns of ortho-substituted fluoronitrobenzenes.
  • Dye and Pigment Intermediate: Acts as a starting material for the synthesis of complex, color-fast dyes and organic pigments.

Basic Information

Product Name 2-Bromo-6-Fluoronitrobenzene
CAS No. 886762-70-5
Molecular Formula C6H3BrFNO2
Molecular Weight 220.00 g/mol
Synonyms 1-Bromo-2-fluoro-3-nitrobenzene; 2-Fluoro-6-bromonitrobenzene; 3-Nitro-2-fluorobromobenzene; Benzene, 1-bromo-2-fluoro-3-nitro-; o-Bromo-o'-fluoronitrobenzene; 2-Bromo-6-fluoronitrobenzene; 2-Fluoro-3-nitrobromobenzene; 886762-70-5
EINECS Contact for details

Quality Control

Every batch of 2-Bromo-6-Fluoronitrobenzene is manufactured and tested under a strict quality management system. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item Specification
Appearance White to light yellow crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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