Description

3,5-Difluoro-4-Bromonitrobenzene is a high-purity halogenated nitrobenzene derivative, serving as a critical multi-functional building block in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and nitro substituents, enables precise molecular modifications essential for creating complex, high-value compounds. This intermediate is primarily sought after by R&D and production chemists in the pharmaceutical, agrochemical, and specialty materials sectors for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic cores to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the difluoro and bromo groups contribute to biological activity and environmental persistence profiles.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form complex biaryl structures.
• Nucleophilic Aromatic Substitution: The activated nitro and fluorine groups allow for selective substitution reactions, enabling the introduction of various amines, alkoxides, and thiols.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	3,5-Difluoro-4-Bromonitrobenzene
CAS No.	886762-62-5
Molecular Formula	C6H2BrF2NO2
Molecular Weight	237.99 g/mol
Synonyms	4-Bromo-3,5-difluoronitrobenzene; 1-Bromo-2,6-difluoro-4-nitrobenzene; Benzene, 1-bromo-2,6-difluoro-4-nitro-; 2,6-Difluoro-4-nitro-1-bromobenzene; 3,5-Difluoro-4-nitro-1-bromobenzene; 886762-62-5; 4-Nitro-3,5-difluorobromobenzene
EINECS	Contact for details

Quality Control

Every batch of 3,5-Difluoro-4-Bromonitrobenzene is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards through rigorous analytical controls, including HPLC, GC, NMR, and mass spectrometry for identity confirmation and purity verification. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.