Description

2,3-Difluoro-4-Methoxyphenylacetonitrile is a high-value, multi-functional fluorinated aromatic nitrile building block. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique substitution pattern enables precise structural modifications. It is primarily sought after by research chemists and process development scientists for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays (LCDs).
• Organic Electronics: Employed in the research and development of organic semiconductors and electro-optical materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) to construct complex biaryl systems.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating novel fluorinated compound libraries.

Basic Information

Product Name	2,3-Difluoro-4-Methoxyphenylacetonitrile
CAS No.	886503-74-8
Molecular Formula	C9H7F2NO
Molecular Weight	183.16 g/mol
Synonyms	2,3-Difluoro-4-methoxybenzyl cyanide; (2,3-Difluoro-4-methoxyphenyl)acetonitrile; 4-Methoxy-2,3-difluorobenzyl cyanide; 2,3-Difluoro-4-methoxybenzeneacetonitrile; 886503-74-8; α-Cyano-2,3-difluoro-4-methoxytoluene; 2-(2,3-Difluoro-4-methoxyphenyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Methoxyphenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.